Overview of Selected Chemical Compounds and Intermediates

Overview of Selected Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected to bortezomib, a proteasome inhibitor Utilized in the procedure of a number of myeloma. Its synthesis or analyze is vital for making sure the purity and safety from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug used in the treatment method of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-1): A essential compound during the synthesis of imatinib, a drug that targets particular sorts of most cancers, together with chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers for instance breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their examine is crucial for optimizing the production procedure and b-D-Ribofuranose ensuring high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is made use of to deal with breast cancer, and these intermediates are associated with its manufacturing.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist used in the therapy of breast cancer. Various intermediates assist in the synthesis of this drug.
Paclitaxel Facet Chain Acid Paclitaxel side chain acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug effective in managing cancers for example ovarian, breast, and lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the procedure of colorectal most cancers and tiny cell lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, which have various apps, like antiviral Qualities.
Vildagliptin Intermediates: Employed in the manufacture of vildagliptin, an oral drug for kind two diabetes that inhibits the enzyme DPP-four to regulate blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is linked to the synthesis of varied gluconic acid derivatives, that are Employed in foods, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor during the synthesis of canagliflozin, a medication utilised to manage variety two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).